Gestational Diabetes similar with type II diabetes. Hormone changes during pregnancy can alter the ability of the body's tolerance to insulin. In early pregnancy (before 20 weeks), the cells are very responsive to insulin, glucose levels in the blood are likely to be lower than usual. It could be the cause of some pregnant women feel nausea and vomiting if there is no food intake over a long period of time.
In diabetes that occurs during pregnancy due to the lack of the amount of insulin produced by the body that is needed to carry glucose across the membrane cells. High levels of blood glucose causes the kidney have to work hard because of increased rate glonurulus filter and decreased ability to reabsorb glucose renalif tubules.
Diabetes can be a hereditary disorder by means of insufficiency or absence of insulin in the blood circulation, high blood sugar concentration. Diabetes in pregnancy raises many difficulties, this disease will lead to changes in metabolic and hormonal to patients who are also affected by pregnancy.
Increased hormones production of pregnancy, especially the Human Placenta Lactogen will increase the resistance of cells to insulin so that it appears the condition of diabetes. Peak effect occurs at the gestational age of about 26 - 28 weeks. The time is a good time doing screening.
Hyperglycemia cause many adverse effects on pregnancy. Figures spontaneous abortion, infant mortality and birth also increased. The death of the blood vessels to the uterus and plesenta thereby increasing uteroplasma insufficiency. In a large number of women also found hypertension and preeclampsia.
Increased maternal blood glucose will be channeled to the fetus through the placenta. The fetus does not suffer diabetes, but it should increase the production of insulin for glucose metabolism. Due to increased levels of insulin and glucose, there was a dramatic physical growth, and causes a large baby (macrosomia). Macrosomia caused by hyperplasia, an increase in the number of cells, hypertrophy, and cell enlargement baby. This condition causes a change that lasts a lifetime for the fetus and proven to increase child and adult obesity, and increase the risk of diabetes in the future.
