Wednesday, April 1, 2015

Diabetes Insipidus

Is it same with diabetes mellitus?

Diabetes insipidus is a disease associated with hormone ADH (anti-diuretic hormone) or its receptor. Hormone ADH acts on the kidneys to concentrate urine, resulting in water and electrolyte balance in the body. If there is a disruption in the production of ADH hormone or its receptor in the kidney problem on, it will create excessive urine production that can lead to dehydration and make people feel thirsty all the time.

diabetes insipidus


Diabetes insipidus and diabetes mellitus are two different diseases and not related. Although both diseases have similar symptoms is polyuria (excessive urine production), but for diabetes insipidus does not contain glucose.

There are two types of diabetes insipidus:

Central diabetes insipidus. The cause is a shortage of production of the hormone ADH.
Diabetes insipidus nefrogenis. The cause was kidney insensitive or does not respond to the anti-diuretic hormone. This results in very dilute urine into and out in considerable amounts.

Symptoms of diabetes insipidus:

Excessive thirst
Excessive urine production
Fatigue-related disorders electrolyte balance
The diagnosis of diabetes insipidus done with lab tests, including:

Urinalysis
Plasma ADH levels
Blood glucose levels, to eliminate the possibility of diabetes mellitus
Blood electrolyte levels
Urine output
Treatment of patients, usually seen from its cause, the usual central type given replacement therapy for hormone ADH. As for the type nefrogenis be seen if there is use of drugs that cause sensitivity to the hormone receptors should be dismissed, usually therapy with adequate fluid intake.

Complications that can occur:

Dehydration
Dry Skin
Weight loss
Fever
Heart rate increased due to electrolyte imbalance
Generally good prognosis in patients when treated quickly, therefore, immediately contact your family physician if you have a complaint in accordance symptoms above.